Website Pfizer

Job Description:

Responsible for the planning and execution of relevant quantitative analyses which may include population pharmacokinetics, pharmacokinetics/pharmacodynamics, exposure response, disease progression modeling, model-based meta analysis, quantitative knowledge management, decision analysis, and EQDD strategy in collaboration with partners.

Job Responsibilities:

  • Prepares formal presentations and written reports to Pfizer standards.
  • Conducts and reports quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development.
  • Provide Quantitative Clinical Pharmacology expertise on multidisciplinary development teams, working closely with clinical pharmacologists, clinicians and statisticians to create clinical development plans that include assessments of a drug’s efficacy, safety, and commercial viability.
  • Contribute to the development or improvement of our tools, processes and methodology, including involvement in internal cross-functional workgroups or initiatives, external alliances or committees, consortia and academic relationships.
  • May help in providing support and/or development of quantitative methodology, pharmacometrics tools, software, hardware, and related business processes
  • Implements model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision-making, in collaboration with partners.
  • Stays abreast of literature, government guidelines, and internal guidance as relates to pharmacometrics and MIDD, including internal SOPs and regulations in order to be a team resource of pharmacometric knowledge and applications.
  • Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety.
  • May contributes with project teams/partners to regulatory documents.

Job Requirements:

  • Other pharmacometric software experience (e.g. Nonmem, PsN, MATLAB)
  • Other statistical software experience (e.g. Stan)
  • Good communication skills (written, oral presentation)
  • Strong quantitative skills (e.g., pharmacometrics, pharmacokinetics, mechanistic modeling/systems pharmacology,
  • literature meta-analyses, clinical trial simulations, statistics).
  • Experience using R software
  • Other programming experience (e.g. Python, C++)
  • We encourage applicants from different disciplines including clinical pharmacology, engineering, biostatistics, medicine, biology, etc.

Job Details:

Company: Pfizer

Vacancy Type: Full Time

Job Location: Toronto, Ontario, CA

Application Deadline: N/A

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